An American team succeeded in reducing the pleasure of eating and increasing the level of exercise in mice, by disabling a specific gene in the brain.
L ‘It is a complex disease that occurs due to several factors: , Hormonal, environmental, life cycle, etc. Therefore, in this concept, only one strategy cannot overcome this . However, we can envision several combined treatments, some of which target genetics as in this study, and others are psychology, Or by targeting the food structural environment of our cities.
at Conducted by researchers from Maryland at National Institute of Health, And deactivate a Very specific eating behavior has drastically changed From . Indeed, in mice whose genes have been inactivated, we can observe a decrease in the attractiveness and consumption of delicious and rewarding foods (meaning that they are particularly stimulating to us. ), And increase your ‘readiness’ for exercise. Can such treatment be considered in humans?
Under the influence of our brain
The eyebrow is a brain structure that forms part of the thalamus that defines the dorsal partFormed from , Habenola and stria . It is an area whose functions are still poorly understood. But scientists are increasingly interested in the granular neural circuit for its potential effects on And the And the And the .
This circuit is under the influence of the action of a specific gene: Prkar2a. Previous experiences have already shown that altering the chordate neural circuit allows thisAlthough subjected to a diet that leads to obesity. In this new experiment, changing this circuit reduces the mice’s attraction to “reward” foods and get them to exercise more, which could be a good thing in obese patients.
Leash in the treatment of obesity?
As we said, obesity is a complex disease. No single strategy can hope to overcome it. But we can imagine thatAn attempt to target this brain circuit could be tested for a little longer in the animal model, in order to measure potential long-term side effects before studies in humans.
In the vast majority of cases, obesity results from an inappropriate environment. It would also be a good idea to focus on structural variables such as our food environment. For example, making raw foods better available and putting them in supermarkets is better than processed foods. In this twenty-first century, the food challenge must be met in many ways. We need to rethink our diets,.
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